Readers Have Questions

In our age of constant interactivity, you could easily see a weekly letter like mine as a quaint one-way monologue. But in fact, I’ve always treated Thoughts from the Frontline as a conversation with friends like you. Sometimes we disagree, but we keep talking.

I get your end of that “we” from the many readers who send me questions and comments. I read them all even when I can’t reply – which is what happens when my letters strike a chord. The e-avalanche responding to just-concluded series on Ray Dalio’s How Countries Go Broke book is a good example.

Today we’ll turn the tables as I respond to you. The Dalio series produced unusually good, thought-provoking questions. I’ll answer some below. But first…

Living Longer, Live Better

One of my top priorities is to keep our dialogue going as long as possible. I want all of us to stay on this mortal coil as long as possible.

I’ve written for years about how we’ve entered a new age in which the science of aging is moving from inside the lab to real life. Over the past decade and especially the last twelve months, as you know, I’ve had a front-row seat. Between opening our new Lifespan Edge clinics and launching the Transformative Age letter, I’ve been absorbing information seemingly faster than ever. I watched friends, readers, and even family members start to benefit from therapies that didn’t exist a decade ago.

Still, some roll their eyes when I bring up “longevity science.” I get it, but it’s not science fiction anymore. From plasma exchange to AI-driven molecule design, to even simple at-home practices like heat therapy and red-light exposure, we’ve entered a new era of biotechnology, one where we can begin to tune our own biological engines and sidestep much of what we used to consider “normal aging.” My friend Dr. Mike Roizen keeps pointing out that YOU are the genetic engineer for yourself. How you live and what you do, the therapies you choose all turn on and turn off specific proteins. And we are now a place that we actually know a great deal about the ones we want to change.

If you’d like to read the story of how this all began and where it’s headed, I just published a reflection here, marking the first anniversary of our biotech and longevity letter, Transformative Age. It’s a look back at how far we’ve come, and a glimpse of where we’re headed next.

What To Do?

My series on Ray Dalio’s book raised a bunch of questions, one of which stood out above the others. To paraphrase, readers asked “How do we get ready for this?” A few examples:

  • “All fascinating. But again, not ONE word of WHAT IS AN INVESTOR SUPPOSED TO DO? Apparently even money market funds are no longer safe! Hope at the end of all this you come up with some sound ideas for the ordinary investor's benefit to protect his assets/purchasing power.

  • “John says we still have some time to prepare - but how?”

  • “Hi John, great article and explanation of the Debt Cycle in our future. Please spend some time in future articles about how to ‘Prepare while you can,’ i.e., good investment areas vs. bad investment areas.”

  • “You wrote there is still time to prepare for the upcoming debt crisis. Please elaborate on methods of preparation.”

To be honest, I invited this when I said the crisis Dalio (and others) expect is probably still a few years off. I described it as a comforting thought; it gives us time to prepare. But I didn’t elaborate, as the readers above rightly noted.